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The results showed that Brineura slowed the decline in motor function and delayed disease onset, according to BioMarin

The serine peptidase catalytic triads, His86, Asp224 and Ser657 in DAP BII 11 and His57, Asp102 and Ser195 21 in chymotrypsin, are almost completely superimposable (Figs

Hippocampal neurons were maintained in Neurobasal A media from Invitrogen (Carlsbad, CA) supplemented with B27 from Invitrogen 0.5 mM L-glutamine, and 5mM cytosme-D-arabinofuranoside from Sigma added at 2 days in vitro

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These molecules have been shown to encourage the formation of new functional synaptic connections, induce long-term potentiation and augment memory consolidation and retrieval in animal models of AD